hello
for flights why don't you use the multi leg option on flight search engines. as an example only, for dept. and rtn in sept, flight 1. london - prague then flight 2. prague - budapest and lastly 3. budapest - london, opodo quotes £322 p/person inclusive of all taxes and booking fees, included in the cost is hold baggage also.
there are a few sites that do this, unfortunatly travelsupermarket.com does not do this.
as for hotels do a search at http://www.travelsupermarket.com/c/hotels/ or a site i use all the time http://www.hotelpricefinder.com/
for tours i use http://www.viator.com/ a very proffesional company who only use some of the best local tour companies.
regards
jim
ps if you have any dates planned i could easily have a quick look for you and give you an idea of cost etc....and get back to you in 24hrs, you could then use that as a starting point and guide for your own search. nearly forgot i could look into airport transfers using public transport (i never get private transfers, ie.. price) for peace of mind i could research private ones or a shuttle transfer direct to the hotel.